Supernatural

Sam Winchester (167 episodes)

Lucifer

Dean Winchester (167 episodes)

Bobby Singer (52 episodes)

Robert 'Bobby' Singer

Castiel (50 episodes)

Leviathan

Jimmy Novak

Himself

Crowley (20 episodes)

Fergus Roderick McLeod

John Winchester (14 episodes)

Ruby (12 episodes)

Herself

Lisa Braeden (11 episodes)

Ellen Harvelle (9 episodes)

Lucifer (9 episodes)

Nick

Samuel Campbell (8 episodes)

Azazel

Kevin Tran (8 episodes)

Zachariah (8 episodes)

Jo Harvelle (7 episodes)

Richard Roman (7 episodes)

Dick Roman

Mary Winchester (7 episodes)

Meg (7 episodes)

Bela Talbot (6 episodes)

Ruby (6 episodes)

Lilith

Meg Masters (6 episodes)

Sheriff Jody Mills (6 episodes)

Anna Milton (6 episodes)

Ben Braeden (6 episodes)

Balthazar (6 episodes)

Chuck Shurley (6 episodes)

Carver Edlund

Benny (5 episodes)

Eli

Young Sam Winchester (5 episodes)

Rufus Turner (5 episodes)

Ash (5 episodes)

Azazel (5 episodes)

Jessica Moore (4 episodes)

FBI Agent Victor Henriksen (4 episodes)

Gordon Walker (4 episodes)

Uriel (4 episodes)

The Trickster (4 episodes)

Gabriel

Pamela Barnes (4 episodes)

Christian Campbell (4 episodes)

Gwen Campbell (4 episodes)

Ed Zeddmore (4 episodes)

Harry Spangler (4 episodes)

Naomi (4 episodes)

Garth (3 episodes)

Garth Fitzgerald IV

Amelia Richardson (3 episodes)

Amelia

Death (3 episodes)

Alastair (3 episodes)

Becky Rosen (3 episodes)

Adam Milligan (3 episodes)

Michael

Tessa (3 episodes)

The Reaper

Alpha Vampire (3 episodes)

Raphael (3 episodes)

Donnie Finnerman